Dr. Jeffrey Ebersole and Linh Nguyen, Ph.D., M.P.H., (both Dental Medicine) co-authored, “,” which published online ahead of print in Journal of Periodontology. The results demonstrated clear gene expression differences in healthy (baseline) tissues between the sexes, with elevations in females associated with immune responses and elevation in males related to tissue structural genes. With disease initiation, fewer genes differed between the sexes, while these differences were significantly increased in progressing disease and resolution, particularly in male animals.
