Jeffrey Ebersole (Dental) co-authored “,” which published in the journal Frontiers in Oral Health. During the study, specific correlations of DAMP/alarmin genes and relative abundance of particular microbes were observed in health and resolution samples in younger animals, while increased correlations during disease in the older groups were noted. Thus, using this human-like preclinical model of induced periodontitis, the authors demonstrated the dynamics of the activation of the DAMP/alarmin warning system in the gingival tissues that showed some specific differences based on age.