Drs. Edward Lynch and Martin Grootveld (both Dental) recently published “Twelve Hour Longevity of the Oral Malodor-Neutralizing Capacity of an Oral Rinse Product Containing the Chlorine Dioxide Precursor Sodium Chlorite” in the international online, open-access, peer-reviewed Journal of Oral Health and Dentistry.
The collaborative study comprised faculty from UNLV School of Dental Medicine and the bioanalytical chemistry and chemical pathology in the biomedical & environmental health department in De Montfort University, United Kingdom.
The study investigated the effectiveness and longevity of an oral rinse product containing 0.10 percent (w/v) of the chlorine dioxide precursor sodium chlorite on oral malodor in participants throughout a 12-hour daylight diurnal cycle. Findings showed the oral rinse effectively blocked VSC production in the oral cavity for a period of 12 hours, likely due to the ability of its active ClO2- ingredient that exerted a combination of biochemical and microbicidal actions in vivo. The product’s longevity of oral malodor-neutralizing actions is clinically significant in view of VSCs involvement, particularly CH3SH, in the pathogenesis of gingivitis and periodontitis.